Some points:
- Have you backed up your personal data?
- Are you experienced in trouble-shooting?
- Are you moving from one LTS to another?
- Have you kept a record of tweaks you've made to the existing system?
- Have you uninstalled ppas and the software they installed?
- Have you installed non-standard kernels on your existing system?
- Did your existing system require drivers not included by default?
- Do you have another machine handy with which you can ask for help?
- Have you tested the new version extensively using a Live USB?
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